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The Energy Landscape, Folding Pathways and the Kinetics of a Knotted Protein

The folding pathway and rate coefficients of the folding of a knotted protein are calculated for a potential energy function with minimal energetic frustration. A kinetic transition network is constructed using the discrete path sampling approach, and the resulting potential energy surface is visual...

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Detalhes bibliográficos
Main Authors: Prentiss, Michael C., Wales, David J., Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895632/
https://ncbi.nlm.nih.gov/pubmed/20617197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000835
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