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Energy landscape of knotted protein folding

Recent experiments have conclusively shown that proteins are able to fold from an unknotted, denatured polypeptide to the knotted, native state without the aid of chaperones. These experiments are consistent with a growing body of theoretical work showing that a funneled, minimally frustrated energy...

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Bibliografske podrobnosti
Main Authors: Sułkowska, Joanna I., Noel, Jeffrey K., Onuchic, Jose N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497829/
https://ncbi.nlm.nih.gov/pubmed/22891304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201804109
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