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Energy landscape of knotted protein folding

Recent experiments have conclusively shown that proteins are able to fold from an unknotted, denatured polypeptide to the knotted, native state without the aid of chaperones. These experiments are consistent with a growing body of theoretical work showing that a funneled, minimally frustrated energy...

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Autores principales: Sułkowska, Joanna I., Noel, Jeffrey K., Onuchic, Jose N.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497829/
https://ncbi.nlm.nih.gov/pubmed/22891304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201804109
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