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Energy landscape of knotted protein folding

Recent experiments have conclusively shown that proteins are able to fold from an unknotted, denatured polypeptide to the knotted, native state without the aid of chaperones. These experiments are consistent with a growing body of theoretical work showing that a funneled, minimally frustrated energy...

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Autors principals: Sułkowska, Joanna I., Noel, Jeffrey K., Onuchic, Jose N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497829/
https://ncbi.nlm.nih.gov/pubmed/22891304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201804109
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