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Dodging the crisis of folding proteins with knots

Proteins with nontrivial topology, containing knots and slipknots, have the ability to fold to their native states without any additional external forces invoked. A mechanism is suggested for folding of these proteins, such as YibK and YbeA, that involves an intermediate configuration with a slipkno...

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Detalhes bibliográficos
Main Authors: Sułkowska, Joanna I., Sułkowski, Piotr, Onuchic, José
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651233/
https://ncbi.nlm.nih.gov/pubmed/19211785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811147106
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