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Dodging the crisis of folding proteins with knots

Proteins with nontrivial topology, containing knots and slipknots, have the ability to fold to their native states without any additional external forces invoked. A mechanism is suggested for folding of these proteins, such as YibK and YbeA, that involves an intermediate configuration with a slipkno...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sułkowska, Joanna I., Sułkowski, Piotr, Onuchic, José
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651233/
https://ncbi.nlm.nih.gov/pubmed/19211785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811147106
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