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Stabilizing effect of knots on proteins

Molecular dynamics studies within a coarse-grained, structure-based model were used on two similar proteins belonging to the transcarbamylase family to probe the effects of the knot in the native structure of a protein. The first protein, N-acetylornithine transcarbamylase, contains no knot, whereas...

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Detalhes bibliográficos
Main Authors: Sułkowska, Joanna I., Sułkowski, Piotr, Szymczak, P., Cieplak, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604914/
https://ncbi.nlm.nih.gov/pubmed/19064918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805468105
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