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Topography of funneled landscapes determines the thermodynamics and kinetics of protein folding
The energy landscape approach has played a fundamental role in advancing our understanding of protein folding. Here, we quantify protein folding energy landscapes by exploring the underlying density of states. We identify three quantities essential for characterizing landscape topography: the stabil...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465441/ https://ncbi.nlm.nih.gov/pubmed/23019359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212842109 |
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