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Topography of funneled landscapes determines the thermodynamics and kinetics of protein folding
The energy landscape approach has played a fundamental role in advancing our understanding of protein folding. Here, we quantify protein folding energy landscapes by exploring the underlying density of states. We identify three quantities essential for characterizing landscape topography: the stabil...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465441/ https://ncbi.nlm.nih.gov/pubmed/23019359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212842109 |
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