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Equilibrium and Kinetic Folding Pathways of a TIM Barrel with a Funneled Energy Landscape

The role of native contact topology in the folding of a TIM barrel model based on the α-subunit of tryptophan synthase (αTS) from Salmonella typhimurium (Protein Data Bank structure 1BKS) was studied using both equilibrium and kinetic simulations. Equilibrium simulations of αTS reveal the population...

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Bibliografiset tiedot
Päätekijät: Finke, John M., Onuchic, José N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Biophysical Society 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366549/
https://ncbi.nlm.nih.gov/pubmed/15833999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.059147
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