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Topography of funneled landscapes determines the thermodynamics and kinetics of protein folding

The energy landscape approach has played a fundamental role in advancing our understanding of protein folding. Here, we quantify protein folding energy landscapes by exploring the underlying density of states. We identify three quantities essential for characterizing landscape topography: the stabil...

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Bibliografische gegevens
Hoofdauteurs: Wang, Jin, Oliveira, Ronaldo J., Chu, Xiakun, Whitford, Paul C., Chahine, Jorge, Han, Wei, Wang, Erkang, Onuchic, José N., Leite, Vitor B.P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465441/
https://ncbi.nlm.nih.gov/pubmed/23019359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212842109
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