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Induction and Bypass of p53 during Productive Infection by Polyomavirus

Lytic infection by polyomavirus leads to elevated levels of p53 and induction of p53 target genes p21Cip1/WAF1 (p21) and BAX. This is seen both in polyomavirus-infected primary mouse cell cultures and in kidney tissue of infected mice. Stabilization of p53 and induction of a p53 response are accompa...

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Detalhes bibliográficos
Main Authors: Dey, Dilip, Dahl, Jean, Cho, Sayeon, Benjamin, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136430/
https://ncbi.nlm.nih.gov/pubmed/12186934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9526-9532.2002
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