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Induction and Bypass of p53 during Productive Infection by Polyomavirus
Lytic infection by polyomavirus leads to elevated levels of p53 and induction of p53 target genes p21Cip1/WAF1 (p21) and BAX. This is seen both in polyomavirus-infected primary mouse cell cultures and in kidney tissue of infected mice. Stabilization of p53 and induction of a p53 response are accompa...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136430/ https://ncbi.nlm.nih.gov/pubmed/12186934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9526-9532.2002 |
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