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Simian Virus 40 Large T Antigen and Two Independent T-Antigen Segments Sensitize Cells to Apoptosis following Genotoxic Damage

The simian virus 40 (SV40) large tumor (T) antigen is sufficient to transform cells in cultures and induce tumors in experimental animals. Transformation of primary cells in cultures requires both overcoming growth arrest by stimulating the cell cycle and blocking cell death activities presumably ac...

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Detalhes bibliográficos
Main Authors: Cole, Sara L., Tevethia, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155145/
https://ncbi.nlm.nih.gov/pubmed/12134045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.8420-8432.2002
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