Induction and Bypass of p53 during Productive Infection by Polyomavirus

Lytic infection by polyomavirus leads to elevated levels of p53 and induction of p53 target genes p21Cip1/WAF1 (p21) and BAX. This is seen both in polyomavirus-infected primary mouse cell cultures and in kidney tissue of infected mice. Stabilization of p53 and induction of a p53 response are accompa...

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izdano v:	J Virol
Principais autores:	Dey, Dilip, Dahl, Jean, Cho, Sayeon, Benjamin, Thomas L.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Virus-Cell Interactions
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9526-9532.2002
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