Induction and Bypass of p53 during Productive Infection by Polyomavirus
Lytic infection by polyomavirus leads to elevated levels of p53 and induction of p53 target genes p21Cip1/WAF1 (p21) and BAX. This is seen both in polyomavirus-infected primary mouse cell cultures and in kidney tissue of infected mice. Stabilization of p53 and induction of a p53 response are accompa...
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| Published in: | J Virol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9526-9532.2002 |
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