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DNA Damage Induces MDMX Nuclear Translocation by p53-Dependent and -Independent Mechanisms
The MDM2 homolog MDMX is an important regulator of p53 activity during embryonic development. MDMX inactivation in mice results in embryonic lethality in a p53-dependent fashion. The expression level of MDMX is not induced by DNA damage, and its role in stress response is unclear. We show here that...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135668/ https://ncbi.nlm.nih.gov/pubmed/12370303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7562-7571.2002 |
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