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DNA Damage Induces MDMX Nuclear Translocation by p53-Dependent and -Independent Mechanisms

The MDM2 homolog MDMX is an important regulator of p53 activity during embryonic development. MDMX inactivation in mice results in embryonic lethality in a p53-dependent fashion. The expression level of MDMX is not induced by DNA damage, and its role in stress response is unclear. We show here that...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Changgong, Chen, Lihong, Chen, Jiandong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC135668/
https://ncbi.nlm.nih.gov/pubmed/12370303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7562-7571.2002
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