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Regulation of p53-MDMX Interaction by Casein Kinase 1 Alpha

MDMX is a homolog of MDM2 that is critical for regulating p53 function during mouse development. MDMX degradation is regulated by MDM2-mediated ubiquitination. Whether there are other mechanisms of MDMX regulation is largely unknown. We found that MDMX binds to the casein kinase 1 alpha isoform (CK1...

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Detalhes bibliográficos
Main Authors: Chen, Lihong, Li, Changgong, Pan, Yu, Chen, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190343/
https://ncbi.nlm.nih.gov/pubmed/16024788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6509-6520.2005
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