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Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding
MDMX is an important regulator of p53 during embryonic development and malignant transformation. Previous studies showed that casein kinase 1α (CK1α) stably associates with MDMX, stimulates MDMX-p53 binding, and cooperates with MDMX to inactivate p53. However, the mechanism by which CK1α stimulates...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497597/ https://ncbi.nlm.nih.gov/pubmed/23028042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00851-12 |
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