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Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

MDMX is an important regulator of p53 during embryonic development and malignant transformation. Previous studies showed that casein kinase 1α (CK1α) stably associates with MDMX, stimulates MDMX-p53 binding, and cooperates with MDMX to inactivate p53. However, the mechanism by which CK1α stimulates...

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Detalhes bibliográficos
Main Authors: Wu, Shaofang, Chen, Lihong, Becker, Andreas, Schonbrunn, Ernst, Chen, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497597/
https://ncbi.nlm.nih.gov/pubmed/23028042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00851-12
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