The p53 Response to DNA Damage In Vivo Is Independent of DNA-Dependent Protein Kinase

Ionizing radiation (IR) exposure causes mammalian cells to undergo p53-dependent cell cycle arrest and/or apoptosis. The in vivo role of DNA-dependent protein kinase (DNA-PK) in the transduction of the DNA damage signal to p53 remains unresolved. To determine the relationship between DNA-PK and p53,...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Jhappan, Chamelli, Yusufzai, Timur M., Anderson, Stacie, Anver, Miriam R., Merlino, Glenn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805749/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.11.4075-4083.2000
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