The p53 Response to DNA Damage In Vivo Is Independent of DNA-Dependent Protein Kinase

Ionizing radiation (IR) exposure causes mammalian cells to undergo p53-dependent cell cycle arrest and/or apoptosis. The in vivo role of DNA-dependent protein kinase (DNA-PK) in the transduction of the DNA damage signal to p53 remains unresolved. To determine the relationship between DNA-PK and p53,...

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Bibliographische Detailangaben
Hauptverfasser: Jhappan, Chamelli, Yusufzai, Timur M., Anderson, Stacie, Anver, Miriam R., Merlino, Glenn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85777/
https://ncbi.nlm.nih.gov/pubmed/10805749
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