Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes

The BRCA1 gene product and its stoichiometric binding partner, BARD1, play a vital role in the cellular response to DNA damage. However, how they acquire specific biochemical functions after DNA damage is poorly understood. Following exposure to genotoxic stress, DNA damage-specific interactions wer...

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Bibliografiske detaljer
Main Authors: Greenberg, Roger A., Sobhian, Bijan, Pathania, Shailja, Cantor, Sharon B., Nakatani, Yoshihiro, Livingston, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356099/
https://ncbi.nlm.nih.gov/pubmed/16391231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1381306
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