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BRCA1 is Required for Post-replication Repair After UV-induced DNA Damage
BRCA1 contributes to the response to UV irradiation. Utilizing its BRCT motifs, it is recruited during S/G2 to UV-damaged sites in a DNA replication-dependent, but nucleotide excision repair- independent manner. More specifically, at UV- stalled replication forks, it promotes photoproduct excision,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200447/ https://ncbi.nlm.nih.gov/pubmed/21963239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.002 |
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