A virus-specific CD8(+) T cell immunodominance hierarchy determined by antigen dose and precursor frequencies

Immunodominance hierarchies are a substantial, but poorly understood, characteristic of CD8(+) T cell-mediated immunity. Factors influencing the differential responses to the influenza A virus nucleoprotein (NP(366–374)) and acid polymerase (PA(224–233)) peptides presented by H2D(b) have been analyz...

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Detalles Bibliográficos
Main Authors: La Gruta, Nicole L., Kedzierska, Katherine, Pang, Ken, Webby, Richard, Davenport, Miles, Chen, Weisan, Turner, Stephen J., Doherty, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1348014/
https://ncbi.nlm.nih.gov/pubmed/16418289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510429103
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