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Contribution of T cell receptor affinity to overall avidity for virus-specific CD8(+) T cell responses

Prior analysis has characterized the clonal characteristics of effector CD8(+) T cells specific for the prominent influenza A virus nucleoprotein (NP) and acid polymerase (PA) peptides presented by H2D(b). Using a single-cell approach and determination of CDR3β profiles, a limited, predominantly “pu...

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Detalhes bibliográficos
Main Authors: Kedzierska, Katherine, La Gruta, Nicole L., Davenport, Miles P., Turner, Stephen J., Doherty, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183580/
https://ncbi.nlm.nih.gov/pubmed/16061802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504851102
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