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TdT is required for the establishment of private virus-specific CD8(+) TCR repertoires and facilitates optimal CTL responses
Virus-immune CD8(+) TCR repertoires specific for particular peptide-MHC class I complexes may be substantially shared between (public), or unique to, individuals (private). Since public TCRs can show reduced terminal deoxynucleotidyl transferase (TdT)-mediated N-region additions, we analysed how TdT...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596983/ https://ncbi.nlm.nih.gov/pubmed/18684946 |
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