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Reproducible selection of high avidity CD8(+) T-cell clones following secondary acute virus infection
The recall of memory CD8(+) cytotoxic T lymphocytes (CTLs), elicited by prior virus infection or vaccination, is critical for immune protection. The extent to which this arises as a consequence of stochastic clonal expansion vs. active selection of particular clones remains unclear. Using a parallel...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910643/ https://ncbi.nlm.nih.gov/pubmed/24474775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323736111 |
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