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Effect of MHCI diversification on influenza epitope-specific CD8(+) T cell precursor frequency and subsequent effector function

Earlier studies of influenza-specific CD8(+) T cell immunodominance hierarchies indicated that expression of the H2K(k) MHCI allele greatly diminishes responses to the H2D(b)-restriced D(b)PA(224) epitope. The results suggested that the presence of H2K(k) during thymic differentiation led to the del...

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Bibliografske podrobnosti
Main Authors: Day, E Bridie, Charlton, Kim L, La Gruta, Nicole L., Doherty, Peter C., Turner, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103778/
https://ncbi.nlm.nih.gov/pubmed/21536802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000883
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