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Effect of MHCI diversification on influenza epitope-specific CD8(+) T cell precursor frequency and subsequent effector function
Earlier studies of influenza-specific CD8(+) T cell immunodominance hierarchies indicated that expression of the H2K(k) MHCI allele greatly diminishes responses to the H2D(b)-restriced D(b)PA(224) epitope. The results suggested that the presence of H2K(k) during thymic differentiation led to the del...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103778/ https://ncbi.nlm.nih.gov/pubmed/21536802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000883 |
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