Novel Gyrase Mutations in Quinolone-Resistant and -Hypersusceptible Clinical Isolates of Mycobacterium tuberculosis: Functional Analysis of Mutant Enzymes

Mutations in the DNA gyrase GyrA(2)GyrB(2) complex are associated with resistance to quinolones in Mycobacterium tuberculosis. As fluoroquinolones are being used increasingly in the treatment of tuberculosis, we characterized several multidrug-resistant clinical isolates of M. tuberculosis carrying...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Aubry, Alexandra, Veziris, Nicolas, Cambau, Emmanuelle, Truffot-Pernot, Chantal, Jarlier, Vincent, Fisher, L. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346799/
https://ncbi.nlm.nih.gov/pubmed/16377674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.104-112.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados