Oxygen-Dependent Ubiquitination and Degradation of Hypoxia-Inducible Factor Requires Nuclear-Cytoplasmic Trafficking of the von Hippel-Lindau Tumor Suppressor Protein

It is becoming increasingly evident that the degradation of nuclear proteins requires nuclear-cytoplasmic trafficking of both the substrate proteins, as well as the E3 ubiquitin-ligases. Here, we show that nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein (VHL) is req...

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Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Groulx, Isabelle, Lee, Stephen
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 2002
Konular:	Nucleocytoplasmic Communication
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12101228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.15.5319-5336.2002
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