Oxygen-Dependent Ubiquitination and Degradation of Hypoxia-Inducible Factor Requires Nuclear-Cytoplasmic Trafficking of the von Hippel-Lindau Tumor Suppressor Protein

It is becoming increasingly evident that the degradation of nuclear proteins requires nuclear-cytoplasmic trafficking of both the substrate proteins, as well as the E3 ubiquitin-ligases. Here, we show that nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein (VHL) is req...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Mol Cell Biol
Huvudupphov:	Groulx, Isabelle, Lee, Stephen
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis 2002
Ämnen:	Nucleocytoplasmic Communication
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12101228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.15.5319-5336.2002
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!