SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation

SOCS-6 is a member of the suppressor of cytokine signaling (SOCS) family of proteins (SOCS-1 to SOCS-7 and CIS) which each contain a central SH2 domain and a carboxyl-terminal SOCS box. SOCS-1, SOCS-2, SOCS-3, and CIS act to negatively regulate cytokine-induced signaling pathways; however, the actio...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Krebs, Danielle L., Uren, Rachel T., Metcalf, Donald, Rakar, Steven, Zhang, Jian-Guo, Starr, Robyn, De Souza, David P., Hanzinikolas, Kathy, Eyles, Jo, Connolly, Lisa M., Simpson, Richard J., Nicola, Nicos A., Nicholson, Sandra E., Baca, Manuel, Hilton, Douglas J., Alexander, Warren S.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2002
Subjects:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12052866/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.13.4567-4578.2002
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