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SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation
SOCS-6 is a member of the suppressor of cytokine signaling (SOCS) family of proteins (SOCS-1 to SOCS-7 and CIS) which each contain a central SH2 domain and a carboxyl-terminal SOCS box. SOCS-1, SOCS-2, SOCS-3, and CIS act to negatively regulate cytokine-induced signaling pathways; however, the actio...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2002
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133908/ https://ncbi.nlm.nih.gov/pubmed/12052866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4567-4578.2002 |
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