Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity

We investigated the influence of telomere proximity and composition on the expression of an EGFP reporter gene in human cells. In transient transfection assays, telomeric DNA does not repress EGFP but rather slightly increases its expression. In contrast, in stable cell lines, the same reporter cons...

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Bibliografische gegevens
Hoofdauteurs: Koering, Catherine Elaine, Pollice, Alessandra, Zibella, Maria Pia, Bauwens, Serge, Puisieux, Alain, Brunori, Michele, Brun, Christine, Martins, Luis, Sabatier, Laure, Pulitzer, John F., Gilson, Eric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
Onderwerpen:
Scientific Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307600/
https://ncbi.nlm.nih.gov/pubmed/12393752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf215
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