Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity

We investigated the influence of telomere proximity and composition on the expression of an EGFP reporter gene in human cells. In transient transfection assays, telomeric DNA does not repress EGFP but rather slightly increases its expression. In contrast, in stable cell lines, the same reporter cons...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koering, Catherine Elaine, Pollice, Alessandra, Zibella, Maria Pia, Bauwens, Serge, Puisieux, Alain, Brunori, Michele, Brun, Christine, Martins, Luis, Sabatier, Laure, Pulitzer, John F., Gilson, Eric
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2002
Gaiak:
Scientific Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307600/
https://ncbi.nlm.nih.gov/pubmed/12393752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf215
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