Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity

We investigated the influence of telomere proximity and composition on the expression of an EGFP reporter gene in human cells. In transient transfection assays, telomeric DNA does not repress EGFP but rather slightly increases its expression. In contrast, in stable cell lines, the same reporter cons...

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Dades bibliogràfiques
Autors principals: Koering, Catherine Elaine, Pollice, Alessandra, Zibella, Maria Pia, Bauwens, Serge, Puisieux, Alain, Brunori, Michele, Brun, Christine, Martins, Luis, Sabatier, Laure, Pulitzer, John F., Gilson, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Scientific Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307600/
https://ncbi.nlm.nih.gov/pubmed/12393752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf215
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