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Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
We investigated the influence of telomere proximity and composition on the expression of an EGFP reporter gene in human cells. In transient transfection assays, telomeric DNA does not repress EGFP but rather slightly increases its expression. In contrast, in stable cell lines, the same reporter cons...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307600/ https://ncbi.nlm.nih.gov/pubmed/12393752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf215 |
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