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Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
We investigated the influence of telomere proximity and composition on the expression of an EGFP reporter gene in human cells. In transient transfection assays, telomeric DNA does not repress EGFP but rather slightly increases its expression. In contrast, in stable cell lines, the same reporter cons...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307600/ https://ncbi.nlm.nih.gov/pubmed/12393752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf215 |
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