Should We Consider Cancers as Embryonic Diseases or as Consequences of Stem-Cell Deregulation?

by Bastid, Jérémy, Puisieux, Alain, Ansieau, Stéphane
Published 2008

Epithelial-mesenchymal transition transcription factors and miRNAs: “Plastic surgeons” of breast cancer

by Moyret-Lalle, Caroline, Ruiz, Emmanuelle, Puisieux, Alain
Published 2014

The cell-of-origin dictates the genomic landscape of breast cancers

by Puisieux, Alain, Pommier, Roxane M., Tissier, Agnès, Morel, Anne-Pierre
Published in Mol Cell Oncol (2017)

Quantifying local malignant adaptation in tissue‐specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level

by Tokutomi, Natsuki, Moyret‐Lalle, Caroline, Puisieux, Alain, Sugano, Sumio, Martinez, Pierre
Published in Evol Appl (2019)

Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity

by Combaret, Valérie, Boyault, Sandrine, Iacono, Isabelle, Brejon, Stéphanie, Rousseau, Raphaël, Puisieux, Alain
Published 2008

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

by Morel, Anne-Pierre, Lièvre, Marjory, Thomas, Clémence, Hinkal, George, Ansieau, Stéphane, Puisieux, Alain
Published 2008

Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer

by Leissner, Philippe, Verjat, Thibault, Bachelot, Thomas, Paye, Malick, Krause, Alexander, Puisieux, Alain, Mougin, Bruno
Published 2006

Interhelical loops within the bHLH domain are determinant in maintaining TWIST1–DNA complexes

by Bouard, Charlotte, Terreux, Raphael, Hope, Jennifer, Chemelle, Julie Anne, Puisieux, Alain, Ansieau, Stéphane, Payen, Léa
Published 2013

Assessing Cell Activities rather than Identities to Interpret Intra-Tumor Phenotypic Diversity and Its Dynamics

by Monteiro, Laloé, Da Silva, Lydie, Lipinski, Boris, Fauvet, Frédérique, Vigneron, Arnaud, Puisieux, Alain, Martinez, Pierre
Published in iScience (2020)

Snail Family Members Unequally Trigger EMT and Thereby Differ in Their Ability to Promote the Neoplastic Transformation of Mammary Epithelial Cells

by Gras, Baptiste, Jacqueroud, Laurent, Wierinckx, Anne, Lamblot, Christelle, Fauvet, Frédérique, Lachuer, Joël, Puisieux, Alain, Ansieau, Stéphane
Published 2014

Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach

by Bouard, Charlotte, Terreux, Raphael, Tissier, Agnès, Jacqueroud, Laurent, Vigneron, Arnaud, Ansieau, Stéphane, Puisieux, Alain, Payen, Léa
Published in BMC Struct Biol (2017)

Modulation of Oxidative Stress by Twist Oncoproteins

by Floc'h, Nicolas, Kolodziejski, Jakub, Akkari, Leila, Simonin, Yannick, Ansieau, Stéphane, Puisieux, Alain, Hibner, Urszula, Lassus, Patrice
Published 2013

Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences

by Bouard, Charlotte, Terreux, Raphael, Honorat, Mylène, Manship, Brigitte, Ansieau, Stéphane, Vigneron, Arnaud M., Puisieux, Alain, Payen, Léa
Published in Nucleic Acids Res (2016)

ABCG2, a novel antigen to sort luminal progenitors of BRCA1(-) breast cancer cells

by Leccia, Felicia, Del Vecchio, Luigi, Mariotti, Elisabetta, Di Noto, Rosa, Morel, Anne-Pierre, Puisieux, Alain, Salvatore, Francesco, Ansieau, Stéphane
Published 2014

Zeb1 expression by tumor or stromal cells is associated with spatial distribution patterns of CD8+ tumor-infiltrating lymphocytes: a hypothesis-generating study on 113 triple negat...

by Ouled Dhaou, Mona, Kossai, Myriam, Morel, Anne-Pierre, Devouassoux-Shisheboran, Mojgan, Puisieux, Alain, Penault-Llorca, Frederique, Radosevic-Robin, Nina
Published in Am J Cancer Res (2020)

Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer

by Fici, Pietro, Gallerani, Giulia, Morel, Anne-Pierre, Mercatali, Laura, Ibrahim, Toni, Scarpi, Emanuela, Amadori, Dino, Puisieux, Alain, Rigaud, Michel, Fabbri, Francesco
Published in Oncotarget (2016)

Upstream ORF affects MYCN translation depending on exon 1b alternative splicing

by Besançon, Roger, Valsesia-Wittmann, Sandrine, Locher, Clara, Delloye-Bourgeois, Céline, Furhman, Lydie, Tutrone, Giovani, Bertrand, Christophe, Jallas, Anne-Catherine, Garin, Elisabeth, Puisieux, Alain
Published 2009

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells()

by Jacqueroud, Laurent, Bouard, Charlotte, Richard, Geoffrey, Payen, Léa, Devouassoux-Shisheboran, Mojgan, Spicer, Douglas B., Caramel, Julie, Collin, Guillaume, Puisieux, Alain, Tissier, Agnès, Ansieau, Stéphane
Published in Neoplasia (2016)

Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity

by Koering, Catherine Elaine, Pollice, Alessandra, Zibella, Maria Pia, Bauwens, Serge, Puisieux, Alain, Brunori, Michele, Brun, Christine, Martins, Luis, Sabatier, Laure, Pulitzer, John F., Gilson, Eric
Published 2002

Influence of Neuroblastoma Stage on Serum-Based Detection of MYCN Amplification

by Combaret, Valerie, Hogarty, Michael D, London, Wendy B, McGrady, Patrick, Iacono, Isabelle, Brejon, Stephanie, Swerts, Katrien, Noguera, Rosa, Gross, Nicole, Rousseau, Raphael, Puisieux, Alain
Published 2009