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Interhelical loops within the bHLH domain are determinant in maintaining TWIST1–DNA complexes

The basic helix-loop-helix (bHLH) transcription factor TWIST1 is essential to embryonic development, and hijacking of its function contributes to the development of numerous cancer types. It forms either a homodimer or a heterodimeric complex with an E2A or HAND partner. These functionally distinct...

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Detalhes bibliográficos
Main Authors: Bouard, Charlotte, Terreux, Raphael, Hope, Jennifer, Chemelle, Julie Anne, Puisieux, Alain, Ansieau, Stéphane, Payen, Léa
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869052/
https://ncbi.nlm.nih.gov/pubmed/23527594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2012.762722
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