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Interhelical loops within the bHLH domain are determinant in maintaining TWIST1–DNA complexes
The basic helix-loop-helix (bHLH) transcription factor TWIST1 is essential to embryonic development, and hijacking of its function contributes to the development of numerous cancer types. It forms either a homodimer or a heterodimeric complex with an E2A or HAND partner. These functionally distinct...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Taylor & Francis
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869052/ https://ncbi.nlm.nih.gov/pubmed/23527594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2012.762722 |
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