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TWIST1 a New Determinant of Epithelial to Mesenchymal Transition in EGFR Mutated Lung Adenocarcinoma

Metastasis is a multistep process and the main cause of mortality in lung cancer patients. We previously showed that EGFR mutations were associated with a copy number gain at a locus encompassing the TWIST1 gene on chromosome 7. TWIST1 is a highly conserved developmental gene involved in embryogenes...

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Autors principals: Pallier, Karine, Cessot, Anatole, Côté, Jean-Francois, Just, Pierre-Alexandre, Cazes, Aurélie, Fabre, Elizabeth, Danel, Claire, Riquet, Marc, Devouassoux-Shisheboran, Mojgan, Ansieau, Stéphane, Puisieux, Alain, Laurent-Puig, Pierre, Blons, Hélène
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260187/
https://ncbi.nlm.nih.gov/pubmed/22272264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029954
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