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Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity

BACKGROUND: Bortezomib, a specific and selective inhibitor of the 26S proteasome with antitumor activity against a wide range of malignancies, has been approved for the treatment of relapsed or refractory multiple myeloma and other cancers. Recently, bortezomib has been identified as an effective in...

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Main Authors: Combaret, Valérie, Boyault, Sandrine, Iacono, Isabelle, Brejon, Stéphanie, Rousseau, Raphaël, Puisieux, Alain
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442611/
https://ncbi.nlm.nih.gov/pubmed/18534018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-50
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