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Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin
Telomeres, repetitive DNA sequences at chromosome ends, are shielded against the DNA damage response (DDR) by the shelterin complex. To understand how shelterin protects telomere ends, we investigated the structural organization of telomeric chromatin in human cells using super-resolution microscopy...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762449/ https://ncbi.nlm.nih.gov/pubmed/26871633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.036 |
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