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Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin

Telomeres, repetitive DNA sequences at chromosome ends, are shielded against the DNA damage response (DDR) by the shelterin complex. To understand how shelterin protects telomere ends, we investigated the structural organization of telomeric chromatin in human cells using super-resolution microscopy...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Bandaria, Jigar N., Qin, Peiwu, Berk, Veysel, Chu, Steven, Yildiz, Ahmet
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762449/
https://ncbi.nlm.nih.gov/pubmed/26871633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.036
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