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Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization
The regulation of telomere length in mammals is crucial for chromosome end-capping and thus for maintaining genome stability and cellular lifespan. This process requires coordination between telomeric protein complexes and the ribonucleoprotein telomerase, which extends the telomeric DNA. Telomeric...
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| Udgivet i: | Nat Rev Mol Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221230/ https://ncbi.nlm.nih.gov/pubmed/33564154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-021-00328-y |
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