Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations

Telomere comprises the ends of eukaryotic linear chromosomes and is composed of G-rich (TTAGGG) tandem repeats which play an important role in maintaining genome stability, premature aging and onsets of many diseases. Majority of the telomere are replicated by conventional DNA replication, and only...

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Gepubliceerd in:Cells
Hoofdauteurs: Amir, Mohd., Khan, Parvez, Queen, Aarfa, Dohare, Ravins, Alajmi, Mohamed F., Hussain, Afzal, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072152/
https://ncbi.nlm.nih.gov/pubmed/32033110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020359
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