Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations

Telomere comprises the ends of eukaryotic linear chromosomes and is composed of G-rich (TTAGGG) tandem repeats which play an important role in maintaining genome stability, premature aging and onsets of many diseases. Majority of the telomere are replicated by conventional DNA replication, and only...

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Vydáno v:Cells
Hlavní autoři: Amir, Mohd., Khan, Parvez, Queen, Aarfa, Dohare, Ravins, Alajmi, Mohamed F., Hussain, Afzal, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072152/
https://ncbi.nlm.nih.gov/pubmed/32033110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020359
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