Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations

Telomere comprises the ends of eukaryotic linear chromosomes and is composed of G-rich (TTAGGG) tandem repeats which play an important role in maintaining genome stability, premature aging and onsets of many diseases. Majority of the telomere are replicated by conventional DNA replication, and only...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Amir, Mohd., Khan, Parvez, Queen, Aarfa, Dohare, Ravins, Alajmi, Mohamed F., Hussain, Afzal, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072152/
https://ncbi.nlm.nih.gov/pubmed/32033110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020359
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