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Asymmetric Structural Motions of the Homomeric α7 Nicotinic Receptor Ligand Binding Domain Revealed by Molecular Dynamics Simulation

A homology model of the ligand binding domain of the α7 nicotinic receptor is constructed based on the acetylcholine-binding protein crystal structure. This structure is refined in a 10 ns molecular dynamics simulation. The modeled structure proves fairly resilient, with no significant changes at th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Henchman, Richard H., Wang, Hai-Long, Sine, Steven M., Taylor, Palmer, McCammon, J. Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303578/
https://ncbi.nlm.nih.gov/pubmed/14581202
Tagiau: Ychwanegu Tag
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