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A gating mechanism proposed from a simulation of a human α7 nicotinic acetylcholine receptor
The nicotinic acetylcholine receptor is a well characterized ligandgated ion channel, yet a proper description of the mechanisms involved in gating, opening, closing, ligand binding, and desensitization does not exist. Until recently, atomic-resolution structural information on the protein was limit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1100735/ https://ncbi.nlm.nih.gov/pubmed/15857954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407739102 |
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