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Nanosecond-Timescale Conformational Dynamics of the Human α7 Nicotinic Acetylcholine Receptor
We explore the conformational dynamics of a homology model of the human α7 nicotinic acetylcholine receptor using molecular dynamics simulation and analyses of root mean-square fluctuations, block partitioning of segmental motion, and principal component analysis. The results reveal flexible regions...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1989720/ https://ncbi.nlm.nih.gov/pubmed/17573436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109843 |
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