Nanosecond-Timescale Conformational Dynamics of the Human α7 Nicotinic Acetylcholine Receptor

We explore the conformational dynamics of a homology model of the human α7 nicotinic acetylcholine receptor using molecular dynamics simulation and analyses of root mean-square fluctuations, block partitioning of segmental motion, and principal component analysis. The results reveal flexible regions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheng, Xiaolin, Ivanov, Ivaylo, Wang, Hailong, Sine, Steven M., McCammon, J. Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biophysical Society 2007
Gaiak:
Biophysical Theory and Modeling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989720/
https://ncbi.nlm.nih.gov/pubmed/17573436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109843
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