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Molecular Dynamics Simulation of the M2 Helices within the Nicotinic Acetylcholine Receptor Transmembrane Domain: Structure and Collective Motions

Multiple nanosecond duration molecular dynamics simulations were performed on the transmembrane region of the Torpedo nicotinic acetylcholine receptor embedded within a bilayer mimetic octane slab. The M2 helices and M2-M3 loop regions were free to move, whereas the outer (M1, M3, M4) helix bundle w...

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Hlavní autoři: Hung, Andrew, Tai, Kaihsu, Sansom, Mark S. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305480/
https://ncbi.nlm.nih.gov/pubmed/15722430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052878
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