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Simulation of the Coupling between Nucleotide Binding and Transmembrane Domains in the ATP Binding Cassette Transporter BtuCD

The nucleotide-induced structural rearrangements in ATP binding cassette (ABC) transporters, leading to substrate translocation, are largely unknown. We have modeled nucleotide binding and release in the vitamin B(12) importer BtuCD using perturbed elastic network calculations and biased molecular d...

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Hlavní autoři: Sonne, Jacob, Kandt, Christian, Peters, Günther H., Hansen, Flemming Y., Jensen, Morten Ø., Tieleman, D. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831707/
https://ncbi.nlm.nih.gov/pubmed/17208973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097972
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