Simulation of the Coupling between Nucleotide Binding and Transmembrane Domains in the ATP Binding Cassette Transporter BtuCD

The nucleotide-induced structural rearrangements in ATP binding cassette (ABC) transporters, leading to substrate translocation, are largely unknown. We have modeled nucleotide binding and release in the vitamin B(12) importer BtuCD using perturbed elastic network calculations and biased molecular d...

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Bibliografiska uppgifter
Huvudupphovsmän: Sonne, Jacob, Kandt, Christian, Peters, Günther H., Hansen, Flemming Y., Jensen, Morten Ø., Tieleman, D. Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2007
Ämnen:
Channels, Receptors, and Electrical Signaling
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831707/
https://ncbi.nlm.nih.gov/pubmed/17208973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097972
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